NCIt definition : A humanized, immunoglobulin G1 monoclonal antibody with potential antitumor activity.
Farletuzumab specifically targets at glycoprotein 3 (GP-3), a cell surface antigen
that is overexpressed on many epithelial-derived cancer cells. Upon binding to the
GP-3 antigen, farletuzumab triggers a host immune response against GP-3 expressing
cells resulting in cell lysis.;