Recombinant Thyrotropin Alfa

Preferred Label : Recombinant Thyrotropin Alfa;

NCIt synonyms : Recombinant TSH Alpha; Recombinant Thyrotropin Alpha; Thyroid Stimulating Hormone Alpha; TSH-alpha;

NCIt related terms : thyrotropin alfa; Thyrogen;

NCIt definition : A recombinant form of the human anterior pituitary glycoprotein thyroid stimulating hormone (TSH) with use in the diagnostic setting. With an amino acid sequence identical to that of human TSH, thyrotropin alfa binds to TSH receptors on normal thyroid epithelial cells or well-differentiated thyroid cancer cells, stimulating iodine uptake and organification, synthesis and secretion of thyroglobulin (Tg), triiodothyronine (T3), and thyroxine (T4).;

Alternative definition : NCI-GLOSS: A form of thyroid-stimulating hormone (TSH) that is made in the laboratory. It is used to test for remaining or recurring cancer cells in patients who have been treated for thyroid cancer.;

UNII : AVX3D5A4LM;

CAS number : 194100-83-9;

Drug name : Thyrogen;

Codes from synonyms : CDR0000386235; CDR0000386234;

Details

Origin ID

C61322;

UMLS CUI

C2587204;

See also inter- (CISMeF)
- Product containing thyrotropin alfa (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Hormone [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing thyrotropin alfa (medicinal product) [SNOMED CT concept]
- Thyrotropin alfa (substance) [SNOMED CT concept]
- Thyrotropin.alpha subunit [LOINC component]
- thyrotropin alfa [ATC Code]
- thyrotropin alfa [MeSH Descriptor]
- thyrotropin alfa [MeSH concept]
Validated automatic mappings to BTNT
- thyrotropin alfa [ATC Code]
Validated automatic mappings to NTBT
- glycoprotein hormones, alpha subunit [MeSH Descriptor]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Thyrotropin Receptor [NCIt concept]

Keyword's position in hierarchy(ies) :

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