IL23A wt Allele

Preferred Label : IL23A wt Allele;

NCIt synonyms : IL23P19; SGRF; Interleukin 23, Alpha Subunit p19 wt Allele; IL-23A; IL-23; P19; Interleukin 23, p19 Subunit; UNQ2498/PRO5798; Interleukin-Six, G-CSF Related Factor Gene;

NCIt definition : Human IL23A wild-type allele is located in the vicinity of 12q13.2 and is approximately 2 kb in length. This allele, which encodes interleukin-23 subunit alpha protein, which is involved in the transcriptional activation of STAT4, the stimulation of cytokine production and immune responses. It has been asserted that certain tumors promote inflammation via IL23A to induce angiogenesis.;

GenBank Accession Number : NM_016584;

Details

Origin ID

C61151;

UMLS CUI

C1881122;

Automatic exact mappings (from CISMeF team)
- Interleukin 23-alpha [OMIM gene]
- Interleukin-23 [MeSH concept]
- Interleukin-23 [MeSH Descriptor]
- Interleukin-23 subunit p19 [MeSH concept]
- cyclin dependent kinase inhibitor 2A [ORDO Gene]
- cyclin dependent kinase inhibitor 2D [ORDO Gene]
- interleukin-23 complex [GO term]
- interleukin-23 receptor binding [GO term]
- interleukin-23 subunit p19 [MeSH Descriptor]
OMIM relation
- Interleukin 23-alpha [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 12q13 [NCIt concept]
gene_is_element_in_pathway
- ATF-2 Transcription Factor Signaling Pathway [NCIt concept]
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- IL23-Mediated Signaling Pathway [NCIt concept]
- Jak-STAT Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Antimicrobial Effect [NCIt concept]
- Cell Proliferation Regulatory Process [NCIt concept]
- Cytokine Receptor Activation [NCIt concept]
- Cytokine Receptor Binding [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Interleukin Signaling Process [NCIt concept]
- NK Cell Activation [NCIt concept]
- T-Cell Activation [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients