" /> Daniplestim - CISMeF





Preferred Label : Daniplestim;

NCIt definition : A synthetic cytokine and interleukin-3 (IL-3) receptor agonist with enhanced hematopoietic potency. Daniplestim exhibits 10- to 20-fold greater biological activity than recombinant human IL-3 in human hematopoietic cell proliferation and marrow colony-forming-unit assays. In contrast, this agent shows no significant increase in pro-inflammatory activity relative to native IL-3. The enhanced hematopoietic activity of daniplestim correlates with a 60-fold increase in IL-3 alpha-subunit binding affinity and 20-fold greater affinity for binding to alpha/beta receptor complexes on intact cells relative to recombinant IL-3.;

UNII : 491EKS8W4C;

CAS number : 161753-30-6;

Drug name : Synthokine;

Molecule name : SC-55494;

Détails


Vous pouvez consulter :


Nous contacter.
30/07/2025


[Accueil] [Haut de page]

© CHU de Rouen. Toute utilisation partielle ou totale de ce document doit mentionner la source.