NCIt definition : A novel semi-synthetic derivative of cyclosporin and a cyclodepsipeptide with chemo-sensitizing
activity. SDZ 280-446 is one of the drug resistance-modifying agents that inhibit
P-glycoprotein, the multidrug resistance efflux pump, thereby restoring the retention
and activities of some drugs in drug-resistant tumor cells.;
CAS number : 129893-84-1; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 129893-84-1
alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo
G-SRS /a ;