Inositol 1,4,5-Trisphosphate

Preferred Label : Inositol 1,4,5-Trisphosphate;

NCIt synonyms : IP3; Inositol 1 4 5-Trisphosphate;

NCIt definition : A phosphatidylinositol with phosphate covalently bound in the 4 and 5 positions of the inositol group. Inositol 1,4,5-trisphosphate acts as an intermediate in the IP3/DAG pathway, hydrolyzed by phospholipase C and liberating diacylglycerol and PIP2, which activate Protein Kinase C and calcium release from the endoplasmic reticulum, respectively.;

CAS number : 85166-31-0;

ChEBI ID : CHEBI:16595;

Details

Origin ID

C580;

UMLS CUI

C0021549;

Currated CISMeF NLP mapping
- inositol 1,4,5-Trisphosphate [MeSH concept]
- inositol 1,4,5-trisphosphate [MeSH Descriptor]
Semantic type(s)
- Biologically Active Substance [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- inositol 1,4,5-Trisphosphate [MeSH concept]
- inositol 1,4,5-trisphosphate [MeSH Descriptor]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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