IgA - CISMeF

Preferred Label : IgA;

NCIt synonyms : Immunoglobulin A;

NCIt definition : IgA is the immunoglobulin subclass that is associated with antibody-mediated mucosal immunity. It is secreted as dimers into the mucosa and is the most effective isotype at fixing complement by the alternative pathway, even though it lacks the ability to fix complement by the classical pathway. There are two subtypes in the human - IgA1 and IgA2.;

Détails

Origin ID

C565;

UMLS CUI

C2825347;

Automatic exact mappings (from CISMeF team)
- CD79a molecule [ORDO Gene]
- Cd79a antigen [OMIM gene]
- Immunoglobulin [FMA entity]
- Immunoglobulin (substance) [SNOMED CT concept]
- Immunoglobulin A [MedDRA LLT]
- Immunoglobulins [MedDRA Preferred Term]
- Immunoglobulins [LOINC component]
- Immunoglobulins [ICD-11 Extension code]
- antigen binding [GO term]
- immunoglobulin [ICPS Descriptor]
- immunoglobulin [IUPAC Term]
- immunoglobulin [COVID-19 Thesaurus concept]
- immunoglobulins [ATC Code]
- immunoglobulins [MeSH Descriptor]
- immunoglobulins [MeSH concept]
Currated CISMeF NLP mapping
- IgA [LOINC component]
- IgA [MedDRA LLT]
- Immunoglobulin A [FMA entity]
- immunoglobulin A [COVID-19 Thesaurus concept]
- immunoglobulin A [MeSH Descriptor]
- immunoglobulin A [MeSH concept]
See also inter- (CISMeF)
- Immunoglobulin A (substance) [SNOMED CT concept]
Semantic type(s)
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Immunoprotein Gene [NCIt concept]
gene_product_has_biochemical_function
- Antibody [NCIt concept]
gene_product_has_chemical_classification
- Protein or Riboprotein Complex [NCIt concept]
gene_product_plays_role_in_biological_process
- Antigen Binding [NCIt concept]
- Immune Response Process [NCIt concept]
- Immune System Process [NCIt concept]
- Mucosal Immunity [NCIt concept]
has_gene_product_element
- Immunoglobulin Heavy Constant Alpha 1 [NCIt concept]
- Immunoglobulin Heavy Constant Alpha 2 [NCIt concept]

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