Prostate Acinar Sarcomatoid Carcinoma

Preferred Label : Prostate Acinar Sarcomatoid Carcinoma;

NCIt synonyms : Sarcomatoid Carcinoma of the Prostate; Prostate Sarcomatoid Carcinoma; Sarcomatoid Carcinoma of Prostate; Prostate Carcinosarcoma;

NCIt related terms : Prostate Sarcomatoid acinar adenocarcinoma;

NCIt definition : A rare acinar adenocarcinoma of the prostate gland with unfavorable prognosis. It is composed of both malignant glandular and sarcomatous components. The sarcomatous component contains a malignant spindle cell proliferation or specific mesenchymal elements including osteosarcoma, chondrosarcoma, and leiomyosarcoma.;

Neoplastic status : Malignant;

Details

Origin ID

C5530;

UMLS CUI

C1335519;

Disease excludes abnormal cell
- Malignant Squamous Cell [NCIt concept]
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
- Neoplastic Squamous Cell [NCIt concept]
Disease may have findings
- Aggressive Clinical Course [NCIt concept]
- Glomerulations [NCIt concept]
- Mucinous Fibroplasia [NCIt concept]
- Perineural Invasion [NCIt concept]
- Prostatic Crystalloids Present [NCIt concept]
- Sarcomatous Component Present [NCIt concept]
- Serum Prostate Specific Antigen Increased [NCIt concept]
- Urinary Retention [NCIt concept]
Has associated anatomic sites
- Genitourinary System [NCIt concept]
- Male Reproductive System [NCIt concept]
- Prostate Gland [NCIt concept]
- Reproductive System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Sarcomatoid carcinoma of the prostate [MedDRA LLT]
concept_is_in_subset
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- Operational Ontology for Radiation Oncology Prostate Cancer Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Mixed Neoplastic Glandular and Squamous Cell Population [NCIt concept]
disease_has_abnormal_cell
- Adenocarcinoma Cell [NCIt concept]
- Malignant Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Malignant Epithelial Spindle Cell [NCIt concept]
- Neoplastic Acinar Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Glandular Cell [NCIt concept]
- Secretory Adenocarcinoma Cell [NCIt concept]
disease_has_finding
- Absence of Basal Cell Layer [NCIt concept]
- Acinar Cell Differentiation [NCIt concept]
- Anaplastic Lesion [NCIt concept]
- Carcinomatous Component Present [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Invasive Lesion [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Poorly Differentiated Lesion [NCIt concept]
disease_has_normal_cell_origin
- Acinar Cell [NCIt concept]
- Epithelial Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Glandular Epithelium [NCIt concept]
- Prostatic Epithelium [NCIt concept]
disease_has_primary_anatomic_site
- Genitourinary System [NCIt concept]
- Male Reproductive System [NCIt concept]
- Prostate Gland [NCIt concept]
disease_mapped_to_gene
- ERG Gene [NCIt concept]
- TMPRSS2/ERG Fusion Gene [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Gain of Chromosome 18q [NCIt concept]
- Gain of Chromosome 1q [NCIt concept]
- Gain of Chromosome 2p [NCIt concept]
- Gain of Chromosome 7 [NCIt concept]
- Gain of Chromosome 8q [NCIt concept]
- Gain of Chromosome Xq [NCIt concept]
- Loss of Chromosome 10q [NCIt concept]
- Loss of Chromosome 13q [NCIt concept]
- Loss of Chromosome 16q [NCIt concept]
- Loss of Chromosome 18q [NCIt concept]
- Loss of Chromosome 1p [NCIt concept]
- Loss of Chromosome 6p [NCIt concept]
- Loss of Chromosome 8p [NCIt concept]
disease_may_have_molecular_abnormality
- ERG Gene Rearrangement [NCIt concept]
- PTEN Gene Inactivation [NCIt concept]
- TMPRSS2-ERG Fusion Protein Expression [NCIt concept]
- TP53 Gene Inactivation [NCIt concept]

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