DLEU2 wt Allele

Preferred Label : DLEU2 wt Allele;

NCIt synonyms : RFP2OS; Non-Protein Coding RNA 22 Gene; LEU2; BCMSUN; MIR15AHG; NCRNA00022; DLB2; LINC00022; Leukemia Associated Gene 2; 1B4; Deleted in Lymphocytic Leukemia, 2 Gene; TRIM13OS; Ret Finger Protein 2 Opposite Strand Gene; Deleted in Lymphocytic Leukemia 2 (Non-Protein Coding) wt Allele; Mir-15a-16-1 Cluster Host Gene (Non-Protein Coding) Gene; Deleted in Lymphocytic Leukemia 2 Gene; Long Intergenic Non-Protein Coding RNA 22 Gene;

NCIt definition : Human DLEU2 wild-type allele is located in the vicinity of 13q14.2 and is approximately 98 kb in length. This allele, which encodes deleted in lymphocytic leukemia 2 non-protein coding RNA, is putatively involved in the inhibition of cancer cell growth. Genetic aberrations involving the gene are associated with B-cell chronic lymphocytic leukemia, mantle-cell lymphoma and multiple myeloma.;

NCIt note : Intron 6 of the DLEU2 gene contains 2 microRNA genes, MIRN15A and MIRN16-1. (OMIM);

GenBank Accession Number : NR_002612;

Details

Origin ID

C54435;

UMLS CUI

C1705129;

OMIM relation
- Deleted in lymphocytic leukemia 2 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_associated_with_disease
- Chronic Lymphocytic Leukemia [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 13: 49554115-49515574 [NCIt concept]
gene_in_chromosomal_location
- 13q14.2 [NCIt concept]
gene_plays_role_in_process
- Cell Proliferation Regulatory Process [NCIt concept]
- Tumor Suppression [NCIt concept]
- Tumorigenesis [NCIt concept]

Keyword's position in hierarchy(ies) :

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