NFE2L2 wt Allele

Preferred Label : NFE2L2 wt Allele;

NCIt synonyms : NRF2; Nuclear Factor (Erythroid-Derived 2)-Like 2 wt Allele;

NCIt definition : Human NFE2L2 wild-type allele is located in the vicinity of 2q31 and is approximately 162 kb in length. This allele, which encodes nuclear factor erythroid 2-related factor 2 protein, is involved in the mediation of transcription by RNA polymerase II.;

NCIt note : The NFE2L2 gene has also been implicated in the regulation of glutathione synthesis, cellular detoxification and cellular antioxidant defense.;

GenBank Accession Number : NM_006164;

Details

Origin ID

C54238;

UMLS CUI

C1709127;

OMIM relation
- Nuclear factor erythroid 2-like 2 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 2q31 [NCIt concept]
gene_is_element_in_pathway
- Oxidative Stress Pathway [NCIt concept]
gene_plays_role_in_process
- DNA Binding [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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