Vascular Endothelial Growth Factor Antisense Oligonucleotide

Preferred Label : Vascular Endothelial Growth Factor Antisense Oligonucleotide;

NCIt synonyms : Vascular Endothelial Cell Growth Factor Antisense Oligonucleotide;

NCIt related terms : vascular endothelial growth factor-antisense oligonucleotide; VEGF-AS;

NCIt definition : An antisense oligonucleotide with potential antiangiogenesis activity. Vascular endothelial growth factor (VEGF) antisense oligonucleotide binds directly to binds VEGF A/C/D mRNA, leading to mRNA degradation and the inhibition of VEGF A-mediated angiogenesis and VEGF C/D-mediated lymphangiogenesis.;

Alternative definition : NCI-GLOSS: A substance that has been studied in the treatment of cancer. It binds to the RNA for a protein called vascular endothelial growth factor (VEGF) that stimulates the growth of new blood vessels. Vascular endothelial growth factor-antisense oligonucleotide blocks the cell's ability to make VEGF, which may kill tumors that need new blood vessels to grow. It is a type of antisense oligonucleotide and a type of gene expression inhibitor.;

Drug name : Veglin;

Codes from synonyms : CDR0000512779; CDR0000468785;

Details

Origin ID

C53435;

UMLS CUI

C1710619;

Automatic exact mappings (from CISMeF team)
- Vascular endothelial growth factor [LOINC component]
- Vascular endothelial growth factor A [LOINC component]
- Vascular endothelial growth factor a [OMIM gene]
- vascular endothelial growth factor A [MeSH concept]
- vascular endothelial growth factor a [MeSH Descriptor]
- vascular endothelial growth factors [MeSH Descriptor]
Semantic type(s)
- Nucleic Acid, Nucleoside, or Nucleotide [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
concept_is_in_subset
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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