Preferred Label : Alfuzosin Hydrochloride;
NCIt synonyms : ( /-)-N-(3-((4-amino-6,7-dimethoxyquinazolin-2-yl)(methyl)amino)propyl)tetrahydrofuran-2-carboxamide
Monohydrochloride; (R,S)-N-[3-[(4-Amino-6,7-dimethoxy-2-quinazolinyl)methylamino] propyl]tetrahydro-2-furancarboxamide
Hydrochloride;
NCIt definition : The hydrochloride salt of alfuzosin, a quinazoline compound with smooth muscle-relaxing
activity. Alfuzosin selectively binds to and antagonizes post-synaptic alpha-1-adrenoreceptors
in smooth muscle of the prostate, bladder base, bladder neck, prostatic capsule, and
prostatic urethra, initiating relaxation of smooth muscle and resulting in improvement
of urine flow and the symptoms of benign prostatic hyperplasia (BPH). This agent also
blocks alpha-1-adrenoreceptors in peripheral vascular smooth muscle, resulting in
vasodilatation and a decrease in peripheral vascular resistance.;
UNII : 75046A1XTN;
InChIKey : YTNKWDJILNVLGX-UHFFFAOYSA-N;
CAS number : 81403-68-1;
Drug name : Uroxatral;
Molecule name : SL 77499-10;
Chemical formula : C19H27N5O4.ClH;
ChEBI ID : CHEBI:32286;
Origin ID : C53408;
UMLS CUI : C0102130;
Semantic type(s)
- Validated automatic mappings to NTBT
- concept_is_in_subset
- has_free_acid_or_base_form
- is_salt_form_of
