Preferred Label : Citrulline;
NCIt synonyms : N5-(Aminocarbonyl)-L-ornithine; 2-Amino-5-(carbamoylamino)pentanoic Acid; L-Citrulline;
NCIt definition : A non-essential amino acid. In hepatocytes, L-citrulline is synthesized in the urea
cycle by the addition of carbon dioxide and ammonia to ornithine. L-citrulline is
converted into L-arginine by the enzymes argininosuccinate synthetase and argininosuccinate
lyase in the presence of L-aspartate and ATP. Subsequently, L-arginine is converted
to nitric oxide by nitric oxide synthase and L-citrulline is regenerated as a by-product.;
UNII : 29VT07BGDA;
InChIKey : RHGKLRLOHDJJDR-BYPYZUCNSA-N;
CAS number : 372-75-8;
Chemical formula : C6H13N3O3;
NSC code : 27425;
ChEBI ID : CHEBI:16349;
Origin ID : C53406;
UMLS CUI : C0008864;
Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
