Preferred Label : Bemiparin Sodium;
NCIt definition : The sodium salt of bemiparin, a second generation, synthetic, low-molecular-weight
heparin (LMWH) with anticoagulant activity. Derived, after depolymerisation and fractionation,
from medical-grade porcine unfractionated heparin (UFH), bemiparin has an average
molecular weight of 3,600 daltons and has a higher anti-factor Xa/anti-factor IIa
ratio (8:1) than first-generation LMWHs. This anticoagulant binds to antithrombin
III, thereby enhancing the inactivation of activated factor X (Factor Xa) and, to
a lesser extent, activated factor II (Factor IIa). Compared to unfractionated heparins,
the use of bemiparin is associated with lower incidences of major bleeding, osteoporosis,
and heparin-induced thrombocytopenia. Bemiparin also promotes a greater release of
tissue factor pathway inhibitor than UFH or dalteparin.;
UNII : P59JKU02CE;
CAS number : 2608411;
Drug name : Badyket; Ivor; Hibor; Zibor;
Origin ID : C53400;
UMLS CUI : C1365493;
Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
- has_free_acid_or_base_form
- is_salt_form_of
