Preferred Label : Bemiparin;
NCIt definition : A second generation, synthetic, low-molecular-weight heparin (LMWH) with anticoagulant
activity. Derived, after depolymerisation and fractionation, from medical-grade porcine
unfractionated heparin (UFH), bemiparin has an average molecular weight of 3,600 daltons
and has a higher anti-factor Xa/anti-factor IIa ratio (8:1) than first-generation
LMWHs. This anticoagulant binds to antithrombin III, thereby enhancing the inactivation
of activated factor X (Factor Xa) and, to a lesser extent, activated factor II (Factor
IIa). Compared to unfractionated heparins, the use of bemiparin is associated with
lower incidences of major bleeding, osteoporosis, and heparin-induced thrombocytopenia.
Bemiparin also promotes a greater release of tissue factor pathway inhibitor than
UFH or dalteparin.;
UNII : PUE0TO3XDR;
NCI Metathesaurus CUI : CL1407473;
Origin ID : C173512;
UMLS CUI : C0916062;
Automatic exact mappings (from CISMeF team)
- Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
- has_salt_form
- is_free_acid_or_base_form_of
