SFRP4 wt Allele

Preferred Label : SFRP4 wt Allele;

NCIt synonyms : frpHE; FRP-4; Secreted Frizzled-Related Protein 4 Gene; Frizzled-Related Protein, Human Endometrium Gene; sFRP-4; PYL; Secreted Frizzled Related Protein 4 wt Allele;

NCIt definition : Human SFRP4 wild type allele is located in the vicinity of 7p14.1 and is approximately 11 kb in length. This allele, which encodes secreted frizzled-related protein 4, is involved in both the initiation of the Wnt protein-mediated signaling pathway, and the regulation of apoptotic gene expression.;

GenBank Accession Number : NM_003014;

Details

Origin ID

C52936;

UMLS CUI

C1705729;

OMIM relation
- Secreted frizzled-related protein 4 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_associated_with_disease
- Hypophosphatemia [NCIt concept]
- Osteomalacia [NCIt concept]
- Rickets [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 7p14.1 [NCIt concept]
gene_is_element_in_pathway
- Wnt Signaling Pathway KEGG [NCIt concept]
gene_plays_role_in_process
- Bone Remodeling [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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