Preferred Label : Rickets;
NCIt related terms : rachitis;
NCIt definition : Bone softening and weakening usually caused by deficiency or impaired metabolism of
vitamin D. Deficiency of calcium, magnesium, or phosphorus may also cause rickets.
It predominantly affects children who suffer from severe malnutrition. It manifests
with bone pain, fractures, muscle weakness, and skeletal deformities.;
Alternative definition : NICHD: A disorder of defective chondrocyte differentiation and mineralization of the
epiphyseal plate due to deficiency of calcium, phosphate, or vitamin D. Rickets can
manifest clinically with features such as craniotabes, costrochondral junction enlargement,
widening of the wrists and ankles, lower extremity bowing, and failure to thrive.
This condition is diagnosed radiographically, and is characterized by growth plate
widening as well as metaphyseal cupping and fraying.;
Codes from synonyms : CDR0000655123; CDR0000660392;
Origin ID : C26878;
UMLS CUI : C0035579;
Currated CISMeF NLP mapping
- DO Cross reference
- False automatic mappings
- Has associated anatomic sites
- Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
- disease_has_associated_gene
- disease_has_normal_tissue_origin
- disease_has_primary_anatomic_site
