GLI1 wt Allele

Preferred Label : GLI1 wt Allele;

NCIt synonyms : Glioma-Associated Oncogene 1 Gene; GLI; Glioma-Associated Oncogene Homolog Gene; Glioma-Associated Oncogene Homolog 1 (Zinc Finger Protein) Gene; GLI Family Zinc Finger 1 wt Allele; GLI wt Allele; PAPA8;

NCIt definition : Human GLI1 wild-type allele is located within 12q13.3 and is approximately 12 kb in length. This allele, which encodes zinc finger protein GLI1, is involved in the modulation of transcription by RNA polymerase II and the regulation of the transcription of specific genes during the development of multiple organ systems.;

NCIt note : The GLI1 gene product plays a role in the development of the central nervous systems and craniofacial, digital, and gastrointestinal features (UniProt/Swiss-Prot).;

GenBank Accession Number : NM_005269;

Details

Origin ID

C52931;

UMLS CUI

C1706548;

OMIM relation
- Gli family zinc finger 1 [OMIM gene]
See also inter- (CISMeF)
- Polydactyly, postaxial, type a8 [OMIM Phenotype]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 12: 56140201-56152312 [NCIt concept]
gene_in_chromosomal_location
- 12q13.3 [NCIt concept]
gene_involved_in_pathogenesis_of_disease
- GLI1-Altered Soft Tissue Tumor [NCIt concept]
gene_is_element_in_pathway
- Basal Cell Carcinoma Pathway [NCIt concept]
- Hedgehog Signaling Events Mediated by Gli Family Proteins [NCIt concept]
- Hedgehog Signaling Pathway [NCIt concept]
- Sonic Hedgehog Pathway [NCIt concept]
gene_plays_role_in_process
- DNA Binding [NCIt concept]
- Pattern Formation [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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