GFI1B wt Allele

Preferred Label : GFI1B wt Allele;

NCIt synonyms : Growth Factor Independence-1B Gene; GFI1B; Growth Factor Independent 1B (Potential Regulator of CDKN1A, Translocated in CML) wt Allele;

NCIt definition : Human GFI1B wild-type allele is located in the vicinity of 9q34.13 and is approximately 46 kb in length. This allele, which encodes growth factor independent protein 1B, may play a role in the modulation of transcription by RNA polymerase II.;

NCIt note : The GFI1B gene product is a potential regulator of the CDKN1A gene product and is translocated to chromosome 22q1 in chronic myelogenous leukemia (GeneCards).;

GenBank Accession Number : NM_004188;

Details

Origin ID

C52920;

UMLS CUI

C1706511;

Automatic exact mappings (from CISMeF team)
- Growth factor-independent 1b [OMIM gene]
- growth factor independent 1B transcriptional repressor [ORDO Gene]
OMIM relation
- Growth factor-independent 1b [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_associated_with_disease
- Chronic Myeloid Leukemia, BCR-ABL1 Positive [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 9: 132883652-132896636 [NCIt concept]
gene_in_chromosomal_location
- 9q34.13 [NCIt concept]
gene_plays_role_in_process
- Blast Cell Proliferation [NCIt concept]
- DNA Binding [NCIt concept]
- Erythropoiesis [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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