BRF1 wt Allele

Preferred Label : BRF1 wt Allele;

NCIt synonyms : TAF3C, Formerly; TAF3B2 Gene; General Transcription Factor 3B, 90-kD Subunit Gene; BRF Gene; BRF1 Homolog, Subunit of RNA Polymerase III Transcription Initiation Factor IIIB (S. cerevisiae) wt Allele; BRF1; TFIIIB90 Gene;

NCIt definition : Human BRF1 wild-type allele is located in the vicinity of 14q and is approximately 92 kb in length. This allele, which encodes transcription factor IIIB 90 kDa subunit protein, plays a role in the transcriptional initiation of small RNA species.;

NCIt note : The BRF1 gene is expressed as two alternatively spliced variants encoding different isoforms, which function at different promoters that are transcribed by RNA polymerase III. (Entrez Gene);

GenBank Accession Number : NM_001519;

Details

Origin ID

C52625;

UMLS CUI

C1705394;

OMIM relation
- Brf1 subunit of rna polymerase III transcription initiation factor [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 14: 104838374-104746670 [NCIt concept]
gene_in_chromosomal_location
- 14q [NCIt concept]
gene_is_element_in_pathway
- RNA Polymerase III Transcription Pathway [NCIt concept]
gene_plays_role_in_process
- DNA Binding [NCIt concept]
- Transcription [NCIt concept]
- Transcription Initiation [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients