CBL wt Allele - CISMeF

Preferred Label : CBL wt Allele;

NCIt synonyms : C-CBL; CBL2; RNF55; Oncogene CBL2 Gene; Casitas B-Lineage Lymphoma Proto-Oncogene Gene; Cas-Br-M Murine Ecotropic Retroviral Transforming Sequence Gene; Casitas B-Lineage Lymphoma Protooncogene Gene; Oncogene CBL Gene; Cbl Proto-Oncogene wt Allele; Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence Gene; FRA11B; NSLL; Fragile Site, Folic Acid Type, Rare, Fra(11)(Q23.3) Gene; Cbl Proto-Oncogene, E3 Ubiquitin Protein Ligase Gene;

NCIt definition : Human CBL wild-type allele is located in the vicinity of 11q23.3 and is approximately 102 kb in length. This allele, which encodes E3 ubiquitin-protein ligase CBL protein, is involved in the regulation of tyrosine kinase receptor degradation.;

NCIt note : An E3 ubiquitin ligase involved in receptor tyrosine kinase degradation;

GenBank Accession Number : NM_005188;

Details

Origin ID

C52501;

UMLS CUI

C1707078;

OMIM relation
- Cbl protooncogene [OMIM gene]
See also inter- (CISMeF)
- Noonan syndrome-like disorder with or without juvenile myelomonocytic leukemia [OMIM Phenotype]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_associated_with_disease
- B-Cell Non-Hodgkin Lymphoma [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 11: 118582196-118675922 [NCIt concept]
gene_in_chromosomal_location
- 11q23.3 [NCIt concept]
gene_involved_in_pathogenesis_of_disease
- Noonan Syndrome-Like Disorder [NCIt concept]
gene_is_element_in_pathway
- Bacterial Invasion of Epithelial Cell Pathway [NCIt concept]
- Chronic Myeloid Leukemia Pathway [NCIt concept]
- EGF Receptor Downregulation by CBL Pathway [NCIt concept]
- ERBB Family Signaling Pathway [NCIt concept]
- Endocytosis Pathway [NCIt concept]
- Ephrin A Forward Signaling Pathway [NCIt concept]
- Erythropoietin Signaling Pathway [NCIt concept]
- FGF Signaling Pathway [NCIt concept]
- Fc-Epsilon Receptor I Signaling Pathway PID [NCIt concept]
- Hepatocyte Growth Factor Receptor Signaling Pathway PID [NCIt concept]
- IL2RB Pathway [NCIt concept]
- IL4-Mediated Signaling Pathway [NCIt concept]
- Insulin Pathway [NCIt concept]
- Insulin/Insulin Receptor Signaling Pathway [NCIt concept]
- Interferon-Gamma Signaling Pathway [NCIt concept]
- Internalization Pathway for Epidermal Growth Factor Receptor [NCIt concept]
- Mast/Stem Cell Growth Factor Receptor Signaling Pathway [NCIt concept]
- PDGFR-beta Signaling Pathway [NCIt concept]
- Sprouty Regulation of Tyrosine Kinase Signaling Pathway [NCIt concept]
- T Cell Receptor Signaling Pathway KEGG [NCIt concept]
- T-Cell Receptor Signaling Pathway in Naive CD4+ T Cells [NCIt concept]
- T-Cell Receptor Signaling Pathway in Naive CD8+ T Cells [NCIt concept]
- Ubiquitin-mediated Proteolysis Pathway [NCIt concept]
- VEGFR1 Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Hematopoietic Process [NCIt concept]
- Signal Transduction [NCIt concept]
- Ubiquitinated Protein Degradation [NCIt concept]
- Ubiquitination [NCIt concept]

Keyword's position in hierarchy(ies) :

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