Preferred Label : Glutathione;
NCIt synonyms : Reduced Glutathione; N-(N-L-gamma-glutamyl-L-cysteinyl)glycine; GSH;
NCIt definition : A tripeptide comprised of three amino acids (cysteine, glutamic acid, and glycine)
present in most mammalian tissue. Glutathione acts as an antioxidant, a free radical
scavenger and a detoxifying agent. Glutathione is also important as a cofactor for
the enzyme glutathione peroxidase, in the uptake of amino acids, and in the synthesis
of leukotrienes. As a substrate for glutathione S-transferase, this agent reacts with
a number of harmful chemical species, such as halides, epoxides and free radicals,
to form harmless inactive products. In erythrocytes, these reactions prevent oxidative
damage through the reduction of methemoglobin and peroxides. Glutathione is also involved
in the formation and maintenance of disulfide bonds in proteins and in the transport
of amino acids across cell membranes.;
Alternative definition : NCI-GLOSS: A substance found in plant and animal tissues that has many functions in
a cell. These include activating certain enzymes and destroying toxic compounds and
chemicals that contain oxygen.;
UNII : GAN16C9B8O;
InChIKey : RWSXRVCMGQZWBV-WDSKDSINSA-N;
CAS number : 70-18-8;
Drug name : Glutham;
Chemical formula : C10H17N3O6S;
NSC code : 400639;
ChEBI ID : CHEBI:16856;
Codes from synonyms : NSC0400639; CDR0000373010; 00267;
Origin ID : C523;
UMLS CUI : C0017817;
See also inter- (CISMeF)
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to BTNT
- Validated automatic mappings to NTBT
- concept_is_in_subset
