NCIt related terms : (S)-2-Aminopentane-dioic acid 5-amide; GLUTAMINE,L-; L-Glutamine;
NCIt definition : A nonessential amino acid. Glutamine can donate the ammonia on its side chain to the
formation of urea (for eventual excretion by the kidneys) and to purines (necessary
for the synthesis of nucleic acids). Glutamic acid-to-glutamine conversion, in which
an ammonia group is added to glutamic acid (catalyzed by glutamine synthase), is of
central importance in the regulation of toxic levels of ammonia in the body. This
agent is a substrate for the production of both excitatory and inhibitory neurotransmitters
(glutamate and GABA) and is also an important source of energy for the nervous system.
Glutamine may become a conditionally essential amino acid during certain catabolic
states.;
Alternative definition : CRCH: Amino acid with side chain -CH2CH2CONH2.; NCI-GLOSS: An amino acid used in nutrition therapy. It is also being studied for the
treatment of diarrhea caused by radiation therapy to the pelvis.;
UNII : 0RH81L854J;
InChIKey : ZDXPYRJPNDTMRX-VKHMYHEASA-N;
CAS number : 56-85-9;
Drug name : Nutrestore; Memoril; Glutaven; Glutacerebro; Resource Glutasolve; Sympt-X G.I.; GlutaSolve; Sympt-X; Glutapak-10; Endari;
Chemical formula : C5H10N2O3;
NSC code : 27421;
ChEBI ID : CHEBI:18050;
Codes from synonyms : NSC0027421; 01854; CDR0000045446; 291;
See also inter- (CISMeF)