KSP Inhibitor SB-743921

Preferred Label : KSP Inhibitor SB-743921;

NCIt related terms : SB-743921;

NCIt definition : A synthetic small molecule with potential antineoplastic properties. SB-743921 selectively inhibits kinesin spindle protein (KSP), an important protein involved in the early stages of mitosis that is expressed in proliferating cells. Inhibition of KSP results in inhibition of mitotic spindle assembly and interrupts cell division, thereby causing cell cycle arrest and induction of apoptosis.;

UNII : 24DSZ1VN92;

InChIKey : PGXYIBJJCLWJST-MUUNZHRXSA-N;

CAS number : 618430-39-0;

Molecule name : SB 743921; SB-743921;

Details

Origin ID

C52199;

UMLS CUI

C1709979;

Currated CISMeF NLP mapping
- SB 743921 [MeSH concept]
- SB 743921 [MeSH Supplementary Concept]
Semantic type(s)
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- SB 743921 [MeSH Supplementary Concept]
- SB 743921 [MeSH concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Kinesin-Like Protein KIF11 [NCIt concept]

Keyword's position in hierarchy(ies) :

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