Preferred Label : Oncotype DX Breast Cancer Assay;

NCIt synonyms : Oncotype DX;

NCIt definition : A diagnostic assay that quantifies the likelihood of breast cancer recurrence in women with newly diagnosed, early stage breast cancer. In addition to predicting distant disease recurrence, Oncotype DX also assesses the benefit from certain types of chemotherapy. The assay, performed using formalin-fixed, paraffin-embedded tumor tissue, analyzes the expression of a panel of 21 genes and the results are provided as a Recurrence Score (0-100). The gene panel was selected and the Recurrence Score calculation was derived through extensive laboratory testing and multiple independent clinical development studies. Oncotype DX is validated for use in breast cancer patients whose disease is newly diagnosed, stage I or II, node-negative, estrogen receptor-positive and who will be treated with tamoxifen.;

Details


Main resources

You can consult :


http://www.inesss.qc.ca/fileadmin/doc/INESSS/Rapports/Oncologie/INESSS_Test_Oncotype_CancerduSein.pdf
http://www.inesss.qc.ca/fileadmin/doc/INESSS/Rapports/Oncologie/INESSS_ANNEXES_Test_Oncotype_CancerduSein.pdf
2016
false
false
false
Canada
French
health technology assessment
carcinoma, ductal, breast
Oncotype DX Breast Cancer Assay
chemotherapy, adjuvant
decision making
risk assessment
predictive value of tests
carcinoma, ductal, breast
gene expression profiling
Molecular Signature
neoplasm recurrence, local
prognosis
practice guidelines as topic
Recurrent Disease, Distant Site

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http://www.e-cancer.fr/Expertises-et-publications/Catalogue-des-publications/Synthese-UPA-PAI-1-ONCOTYPE-DXtm-MAMMAPRINT-R-Valeurs-pronostique-et-predictive-pour-une-utilite-clinique-dans-la-prise-en-charge-du-cancer-du-sein
2014
false
France
French
technical report
predictive value of tests
molecular diagnostic techniques
breast neoplasms
Biomarkers, Tumor
prognosis
comparative study
breast neoplasms
MammaPrint
Oncotype DX Breast Cancer Assay

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07/07/2025


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