PRIM1 wt Allele

Preferred Label : PRIM1 wt Allele;

NCIt synonyms : Primase, Polypeptide 1, 49kDa wt Allele; p49;

NCIt definition : Human PRIM1 wild-type allele is located within 12q13 and is approximately 21 kb in length. This allele, which encodes DNA primase small subunit protein, is involved in the synthesis of small RNA primers utilized during discontinuous DNA replication.;

NCIt note : The PRIM1 gene has been shown to be amplified in osteosarcoma.;

GenBank Accession Number : NM_000946;

Details

Origin ID

C52050;

UMLS CUI

C1709430;

Automatic exact mappings (from CISMeF team)
- Serum response factor binding protein 1 [OMIM gene]
OMIM relation
- Primase polypeptide 1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 12q13 [NCIt concept]
gene_is_element_in_pathway
- DNA Replication Pathway [NCIt concept]
- Purine Metabolism Pathway [NCIt concept]
- Pyrimidine Metabolism Pathway [NCIt concept]
gene_plays_role_in_process
- DNA Binding [NCIt concept]
- DNA Replication [NCIt concept]

Keyword's position in hierarchy(ies) :

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