INHBB wt Allele

Preferred Label : INHBB wt Allele;

NCIt synonyms : Inhibin, Beta B (Activin AB Beta Polypeptide) wt Allele;

NCIt definition : Human INHBB wild-type allele is located within 2cen-q13 and is approximately 6 kb in length. This allele, which encodes inhibin beta B chain protein, is involved in the both the promotion and inhibition of follitropin secretion in the pituitary gland. It also plays a role in the regulation of diverse cellular functions.;

NCIt note : It has been proposed that loss of INHBB gene expression in pheochromocytomas may be used as an indicator of malignant potential.;

GenBank Accession Number : NM_002193;

Details

Origin ID

C52048;

UMLS CUI

C1708446;

OMIM relation
- Inhibin, beta b [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_has_physical_location
- 2: 120819229-120825204 [NCIt concept]
gene_in_chromosomal_location
- 2cen-q13 [NCIt concept]
gene_is_element_in_pathway
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- TGF-beta Signaling Pathway KEGG [NCIt concept]
gene_plays_role_in_process
- Cell Proliferation Regulatory Process [NCIt concept]
- Regulation of Exocytosis [NCIt concept]

Keyword's position in hierarchy(ies) :

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