" /> VEGFA wt Allele - CISMeF





Preferred Label : VEGFA wt Allele;

NCIt synonyms : VEGF-A; VPF; Vascular Endothelial Growth Factor A wt Allele; MGC70609; VEGF; VEGF wt Allele;

NCIt definition : Human VEGFA wild-type allele is located within 6p12 and is approximately 16 kb in length. This allele, which encodes vascular endothelial growth factor A protein, plays a role in several processes related to vasculature function, including angiogenesis. The allele is also involved in endothelial cell growth cell migration and apoptotic inhibition.;

NCIt note : The VEGF Gene (PDGF/VEGF Family) at 6p12 encodes seven alternatively spliced isoforms of Vascular Endothelial Growth Factor: VEGF206, VEGF189, VEGF183, VEGF165/VEGF, VEGF148, VEGF145, and VEGF121. This gene is regulated by growth factors, cytokines, gonadotropins, nitric oxide, hypoxia, and hypoglycemia. Expression is induced by hypoxia and E2 regulates transcription through a variant upstream ERE.; Isoforms: VEGF206, VEGF189, VEGF183, VEGF165/VEGF, VEGF148, VEGF145, VEGF121;

GenBank Accession Number : NM_003376;

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29/07/2025


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