THPO wt Allele

Preferred Label : THPO wt Allele;

NCIt synonyms : MKCSF; MPLLG Gene; TPO Gene; Thrombopoietin wt Allele; MGDF Gene; Thrombopoietin (Myeloproliferative Leukemia Virus Oncogene Ligand, Megakaryocyte Growth and Development Factor) Gene; ML; THCYT1;

NCIt definition : Human THPO wild-type allele is located within 2p13 and is approximately 107 kb in length. This allele, which encodes thrombopoietin protein, plays a role in megakaryocyte proliferation and maturation, as well as thrombopoiesis.;

GenBank Accession Number : NM_000460;

Details

Origin ID

C51525;

UMLS CUI

C1705224;

Automatic exact mappings (from CISMeF team)
- Machine Learning [MeSH Descriptor]
- Milliliter (qualifier value) [SNOMED CT concept]
- Rare lymphatic malformation [ORDO Disease]
- Thrombocythemia 1 [OMIM Phenotype]
- Thrombopoietin [OMIM gene]
- lymphangioma [MeSH Descriptor]
OMIM relation
- Thrombopoietin [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 3q26.3-q27 [NCIt concept]
gene_is_element_in_pathway
- Hematopoietic Cell Lineage Pathway [NCIt concept]
- TPO Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Cell Differentiation Process [NCIt concept]
- Cytokine Receptor Activation [NCIt concept]
- Cytokine Receptor Binding [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Hematopoietic Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Megakaryocyte Proliferation [NCIt concept]
- Thrombopoiesis [NCIt concept]

Keyword's position in hierarchy(ies) :

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