" /> DNTT wt Allele - CISMeF





Preferred Label : DNTT wt Allele;

NCIt synonyms : TDT; Deoxynucleotidyltransferase, Terminal wt Allele;

NCIt definition : Human DNTT wild-type allele is located within 10q23-q24 and is approximately 34 kb in length. This allele, which encodes DNA nucleotidylexotransferase protein, plays a role in the template direction-independent addition of deoxyribonucleotides to the 3'-hydroxyl terminus of oligonucleotide primers.;

NCIt note : The DNTT gene is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation. DNA nucleotidylexotransferase protein is a specific marker for the diagnosis and classification of lymphoblastic lymphoma.;

GenBank Accession Number : NM_004088;

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11/05/2024


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