CCR1 wt Allele

Preferred Label : CCR1 wt Allele;

NCIt synonyms : MIP1aR Gene; CKR-1 Gene; Chemokine (C-C Motif) Receptor 1 wt Allele; CC-CKR-1 Gene; C-C Chemokine Receptor Type 1 Gene; CMKBR1 Gene; CCR-1 Gene; C-C CKR-1 Gene; HM145 Gene; RANTES-R Gene; CMKR1 Gene; Macrophage Inflammatory Protein-1 Alpha Receptor Gene; RANTES Receptor Gene; LD78 Receptor Gene; MIP-1Alpha-R Gene; Chemokine, CC Motif, Receptor 1 Gene; SCYAR1; CKR1; CD191;

NCIt definition : Human CCR1 wild-type allele is located within 3p21 and is approximately 6 kb in length. This allele, which encodes C-C chemokine receptor type 1 protein, is involved in signal transduction and recruitment of effector immune cells to the site of inflammation. This allele has purported roles in host protection from inflammatory responses, and susceptibility to virus and parasite invasion.;

GenBank Accession Number : NM_001295;

Details

Origin ID

C51318;

UMLS CUI

C1707090;

Automatic exact mappings (from CISMeF team)
- C-C motif chemokine receptor 1 [ORDO Gene]
- Chemokine, CC motif, receptor 1 [OMIM gene]
- chemokine ccl3 [MeSH Descriptor]
- receptors, ccr1 [MeSH Descriptor]
OMIM relation
- Chemokine, CC motif, receptor 1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 3: 46224820-46218720 [NCIt concept]
gene_in_chromosomal_location
- 3p21 [NCIt concept]
gene_is_element_in_pathway
- Chemokine Signaling Pathway [NCIt concept]
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- T-Cell Polarization Pathway [NCIt concept]
gene_plays_role_in_process
- Chemotactic Process [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Immunoregulation [NCIt concept]
- Inflammatory Response [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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