Folate Antagonist

Preferred Label : Folate Antagonist;

NCIt synonyms : Folic Acid Inhibitors; Folate Inhibitors; Folic Acid Antagonist; Folate Analog; Folic Acid Antagonists; Folic Acid Analog; Antifolates;

NCIt related terms : antifolate;

NCIt definition : A compound with a chemical structure similar to folic acid. Folate antagonists inhibit one or more folate-dependent enzymes, resulting in decreased DNA, RNA and protein synthesis.;

Alternative definition : NCI-GLOSS: A substance that blocks the activity of folic acid. Folate antagonists are used to treat cancer.;

Codes from synonyms : CDR0000044815; CDR0000044814;

Details

Origin ID

C511;

UMLS CUI

C0016411;

Currated CISMeF NLP mapping
- Antifolate (substance) [SNOMED CT concept]
- Folic acid antagonist [ICD-11 Extension code]
- Folic acid antagonist [ICHI extension code]
- folic acid antagonists [MeSH Descriptor]
- folic acid antagonists [MeSH concept]
False automatic mappings
- folic acid analogues [ATC Code]
See also inter- (CISMeF)
- Product containing antifolate (product) [SNOMED CT concept]
Semantic type(s)
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Antifolate (substance) [SNOMED CT concept]
- Folic acid antagonist [ICD-11 Extension code]
- Product containing antifolate (product) [SNOMED CT concept]
- folic acid antagonists [MeSH concept]
- folic acid antagonists [MeSH Descriptor]

Keyword's position in hierarchy(ies) :

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