FES wt Allele - CISMeF

Preferred Label : FES wt Allele;

NCIt synonyms : Feline Sarcoma Oncogene wt Allele; FPS;

NCIt definition : Human FES wild-type allele is located in the vicinity of 15q26.1 and is approximately 11 kb in length. This allele, which encodes proto-oncogene tyrosine-protein kinase Fes/Fps protein, plays a role in signal transduction. The FES gene is translocated in acute promyelocytic leukemia.;

NCIt note : The FES gene undergoes alternative splicing to produce twelve transcript variants and twelve corresponding distinct protein isoforms.;

GenBank Accession Number : NM_002005;

Details

Origin ID

C51076;

UMLS CUI

C1708010;

Automatic exact mappings (from CISMeF team)
- Farnesyl diphosphate synthase [OMIM gene]
- Fes protooncogene, tyrosine kinase [OMIM gene]
- Fontaine progeroid syndrome [OMIM Phenotype]
- sn-glycerol-3-phosphate 2-alpha-galactosyltransferase activity [GO term]
OMIM relation
- Fes protooncogene, tyrosine kinase [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 15q26.1 [NCIt concept]
gene_is_element_in_pathway
- Angiopoietin-1 Receptor Signaling Pathway [NCIt concept]
- Axon Guidance Pathway [NCIt concept]
- IL4-Mediated Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Cell Differentiation Process [NCIt concept]
- Cell Growth [NCIt concept]
- Cell Proliferation [NCIt concept]
- Hematopoietic Process [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Signal Transduction [NCIt concept]
- Tyrosine Phosphorylation [NCIt concept]

Keyword's position in hierarchy(ies) :

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