FER wt Allele - CISMeF

Preferred Label : FER wt Allele;

NCIt synonyms : Fer (FPS/FES Related) Tyrosine Kinase (Phosphoprotein NCP94) wt Allele; TYK3; FerT; PPP1R74;

NCIt definition : Human FER wild-type allele is located within 5q21 and is approximately 440 kb in length. This allele, which encodes proto-oncogene tyrosine-protein kinase FER protein, is involved in signal transduction.;

NCIt note : In a mechanism involving growth factor receptors, proto-oncogene tyrosine-protein kinase FER protein mediates signaling from the cell surface to the cytoskeleton. The FER gene may play a role in the regulation of innate immunity.;

GenBank Accession Number : NM_005246;

Details

Origin ID

C51074;

UMLS CUI

C1708009;

Automatic exact mappings (from CISMeF team)
- Fertility studies [LOINC component]
- Fertility testing [LOINC Class]
- Fps/fes-related tyrosine kinase [OMIM gene]
OMIM relation
- Fps/fes-related tyrosine kinase [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 5: 108111422-108551272 [NCIt concept]
gene_in_chromosomal_location
- 5q21 [NCIt concept]
gene_is_element_in_pathway
- Adherens Junction Assembly Pathway [NCIt concept]
- Fc-Epsilon Receptor I Signaling Pathway PID [NCIt concept]
- Mast/Stem Cell Growth Factor Receptor Signaling Pathway [NCIt concept]
- N-Cadherin Signaling Pathway [NCIt concept]
- PTPN1 Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Cell Adhesion Process [NCIt concept]
- Cell Differentiation Process [NCIt concept]
- Cell Growth [NCIt concept]
- Cell Proliferation [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Signal Transduction [NCIt concept]
- Tyrosine Phosphorylation [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients