MAGI1 wt Allele

Preferred Label : MAGI1 wt Allele;

NCIt synonyms : MAGI-1; AIP3; Membrane Associated Guanylate Kinase, WW and PDZ Domain Containing 1 wt Allele; TNRC19; BAIAP1; WWP3; BAP1; Membrane-Associated Guanylate Kinase, WW and PDZ Domains-Containing, 1 Gene; BAP-1; Trinucleotide Repeat-Containing Gene 19; BAIAP1 wt Allele; Magi1d; AIP-3;

NCIt definition : Human MAGI1 wild-type allele is located in the vicinity of 3p14.1 and is approximately 682 kb in length. This allele, which encodes membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1, plays a role in protein binding, structural support and cell adhesion at tight junctions in epithelial cells.;

NCIt note : Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 interacts with the PTEN tumor suppressor protein to form a signalosome that stabilizes the adherens junctions of epithelial cells and inhibits the invasiveness of tumor cells.;

GenBank Accession Number : NM_004742;

Details

Origin ID

C51055;

UMLS CUI

C1704462;

OMIM relation
- Membrane-associated guanylate kinase, ww and pdz domains-containing, 1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 3: 65999265-65321090 [NCIt concept]
gene_in_chromosomal_location
- 3p14.1 [NCIt concept]
gene_is_element_in_pathway
- Tight Junction Assembly Pathway [NCIt concept]
gene_plays_role_in_process
- Cell Proliferation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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