Colorectal Adenocarcinoma

Preferred Label : Colorectal Adenocarcinoma;

NCIt synonyms : Adenocarcinoma of Large Bowel; Adenocarcinoma of Large Intestine; Large Intestine Adenocarcinoma; Large Bowel Adenocarcinoma; Adenocarcinoma of the Large Intestine; Adenocarcinoma of the Large Bowel;

NCIt related terms : Colorectal (Colon or Rectal) Adenocarcinoma;

NCIt definition : The most common type of colorectal carcinoma. It is characterized by the presence of malignant glandular epithelial cells invading through the muscularis mucosa into the submucosa. Histologic variants include mucinous adenocarcinoma, signet ring cell carcinoma, medullary carcinoma, serrated adenocarcinoma, cribriform comedo-type adenocarcinoma, and micropapillary adenocarcinoma.;

Neoplastic status : Malignant;

Details

Origin ID

C5105;

UMLS CUI

C1319315;

Automatic exact mappings (from CISMeF team)
- Adenocarcinoma of large intestine (disorder) [SNOMED CT concept]
- Adenocarcinoma of the large intestine [HPO term]
- colo rectal cancer [Artificial nutrition thesaurus concept]
- large intestine adenocarcinoma [DO Concept]
Currated CISMeF NLP mapping
- Colorectal adenocarcinoma [PASCAL descriptor]
- Colorectal adenocarcinoma [MedDRA Preferred Term]
- colorectal adenocarcinoma [DO Concept]
- colorectal adenocarcinoma [Disease (Nov.)]
DO Cross reference
- colorectal adenocarcinoma [DO Concept]
Disease excludes abnormal cell
- Malignant Squamous Cell [NCIt concept]
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
- Neoplastic Squamous Cell [NCIt concept]
Disease may have findings
- Lower Gastrointestinal Hemorrhage [NCIt concept]
Has associated anatomic sites
- Colorectal Region [NCIt concept]
- Digestive System [NCIt concept]
- Intestine [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Adenocarcinoma of large intestine (disorder) [SNOMED CT concept]
- Adenocarcinoma of the large intestine [HPO term]
- Colorectal adenocarcinoma [PASCAL descriptor]
- Colorectal adenocarcinoma [MedDRA Preferred Term]
- colorectal adenocarcinoma [DO Concept]
- colorectal adenocarcinoma [Disease (Nov.)]
- large intestine adenocarcinoma [DO Concept]
Validated automatic mappings to BTNT
- large intestine adenocarcinoma [DO Concept]
associated_with_malfunction_of_gene_product
- CUB and Sushi Domain-Containing Protein 1 [NCIt concept]
- Mothers Against Decapentaplegic Homolog 3 [NCIt concept]
concept_is_in_subset
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- Cellosaurus Disease Terminology [NCIt concept]
- Cellosaurus Terminology [NCIt concept]
- NCIt Neoplasm Core Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Intermediate Grade Neuroendocrine Lesion [NCIt concept]
- Low Grade Neuroendocrine Lesion [NCIt concept]
- Mixed Neoplastic Glandular and Squamous Cell Population [NCIt concept]
- Well Differentiated Neuroendocrine Lesion [NCIt concept]
disease_has_abnormal_cell
- Adenocarcinoma Cell [NCIt concept]
- Malignant Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Glandular Cell [NCIt concept]
disease_has_associated_gene
- CSMD1 Gene [NCIt concept]
- CSMD1 wt Allele [NCIt concept]
disease_has_finding
- Carcinomatous Component Present [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
- Glandular Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Glandular Epithelium [NCIt concept]
- Large Intestinal Mucosa [NCIt concept]
disease_has_primary_anatomic_site
- Colorectal Region [NCIt concept]
- Digestive System [NCIt concept]
disease_mapped_to_gene
- APC Gene [NCIt concept]
- BRAF Gene [NCIt concept]
- KRAS Gene [NCIt concept]
- TP53 Gene [NCIt concept]
disease_may_have_molecular_abnormality
- BRAF Gene Mutation [NCIt concept]
- Inactivating APC Gene Mutation [NCIt concept]
- KRAS Gene Amplification [NCIt concept]
- MYC Gene Mutation [NCIt concept]
- TP53 Gene Inactivation [NCIt concept]
may_be_associated_disease_of_disease
- Anal Canal Paget Disease [NCIt concept]
- Anal Margin Paget Disease [NCIt concept]
- Anal Paget Disease [NCIt concept]
- Recurrent Paget Disease of the Anal Canal [NCIt concept]

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