IMPDH2 wt Allele

Preferred Label : IMPDH2 wt Allele;

NCIt synonyms : IMPD2; IMP (Inosine Monophosphate) Dehydrogenase 2 wt Allele;

NCIt definition : Human IMPDH2 wild-type allele is located in the vicinity of 3p21.2 and is approximately 5 kb in length. This allele, which encodes Inosine-5'-monophosphate dehydrogenase 2 protein, plays a role in de novo guanine nucleotide synthesis.;

NCIt note : IMPDH2 gene expression is elevated in some tumors, suggesting that it may contribute to malignant transformation.;

GenBank Accession Number : NM_000884;

Details

Origin ID

C50889;

UMLS CUI

C1708442;

OMIM relation
- Imp dehydrogenase 2 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 3: 49041832-49036767 [NCIt concept]
gene_in_chromosomal_location
- 3p21.2 [NCIt concept]
gene_is_element_in_pathway
- Drug Metabolism by Non-CYP450 Enzymes Pathway [NCIt concept]
- Purine Metabolism Pathway [NCIt concept]
gene_plays_role_in_process
- Nucleotide Metabolic Process [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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