Imp dehydrogenase 2

Preferred Label : Imp dehydrogenase 2;

Symbol : IMPDH2;

CISMeF acronym : IMPDHII; IMPD2; IMPDH2;

Type : Gene;

Alternative titles and symbols : Inosine-5-prime-monophosphate dehydrogenase, type II; IMPD2; IMPDHII;

Description : Human type II inosine 5-prime-monophosphate dehydrogenase (EC 1.1.1.205) is the rate-limiting enzyme in de novo guanine nucleotide biosynthesis. Regulated inosine 5-prime-monophosphate dehydrogenase activity is associated with cellular proliferation, transformation, and differentiation (Glesne and Huberman, 1994). See also IMP dehydrogenase-1 (IMPDH1; 146690).;

Ensembl ID : ENSG00000178035;

Prefixed ID : *146691;

Details

Origin ID

146691;

UMLS CUI

C1416428;

Automatic exact mappings (from CISMeF team)
- IMPDH2 Gene [NCIt concept]
- IMPDH2 wt Allele [NCIt concept]
- inosine monophosphate dehydrogenase 2 [HGNC gene]
Currated CISMeF NLP mapping
- Inosine-5'-Monophosphate Dehydrogenase 2 [NCIt concept]
HGNC gene
- inosine monophosphate dehydrogenase 2 [HGNC gene]
NCIt concept(s)
- IMPDH2 Gene [NCIt concept]
- IMPDH2 wt Allele [NCIt concept]
- Inosine-5'-Monophosphate Dehydrogenase 2 [NCIt concept]
ORDO concept(s)
- inosine monophosphate dehydrogenase 2 [ORDO Gene]
Phenotypes related
- Impdh2 enzyme activity, variation in [OMIM Phenotype]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
UMLS correspondences (same concept)
- IMPDH2 Gene [NCIt concept]
- inosine monophosphate dehydrogenase 2 [HGNC gene]

Keyword's position in hierarchy(ies) :

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