TOP3B wt Allele

Preferred Label : TOP3B wt Allele;

NCIt synonyms : Topoisomerase (DNA) III Beta 180kDa wt Allele;

NCIt definition : Human TOP3B wild-type allele is located in the vicinity of 22q11.22 and is approximately 26 kb in length. This allele, which encodes DNA topoisomerase 3-beta-1 protein, is involved in the ATP-independent breakage of negatively supercoiled single-stranded DNA and subsequent passage/rejoining of the broken DNA.;

GenBank Accession Number : NM_003935;

Details

Origin ID

C50386;

UMLS CUI

C1706147;

OMIM relation
- Topoisomerase, dna, III, beta [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 22q11.22 [NCIt concept]
gene_is_element_in_pathway
- Homologous Recombination Pathway [NCIt concept]
gene_plays_role_in_process
- Cell Aging [NCIt concept]
- DNA Maintenance [NCIt concept]
- DNA Recombination Process [NCIt concept]
- Transcription [NCIt concept]

Keyword's position in hierarchy(ies) :

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