MMP14 wt Allele

Preferred Label : MMP14 wt Allele;

NCIt synonyms : MTMMP1; MMP-X1; MT1-MMP; Matrix Metalloproteinase 14 (Membrane-Inserted) wt Allele; Matrix Metalloproteinase 14, Membrane-Type Gene;

NCIt definition : Human MMP14 wild-type allele is located within 14q11-q12 and is approximately 11 kb in length. This allele, which encodes matrix metalloproteinase-14, plays a role in the activation of progelatinase A. The MMP14 gene is associated with the metastasis of several types of cancer including breast, gastric and laryngeal cancers.;

GenBank Accession Number : NM_004995;

Details

Origin ID

C49730;

UMLS CUI

C1704883;

OMIM relation
- Matrix metalloproteinase 14 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 14: 22375633-22386643 [NCIt concept]
gene_in_chromosomal_location
- 14q11-q12 [NCIt concept]
gene_is_element_in_pathway
- Gonadotropin-Releasing Hormone Signaling Pathway [NCIt concept]
- Inhibition of Matrix Metalloproteinases Pathway [NCIt concept]
gene_plays_role_in_process
- Hydrolysis [NCIt concept]
- Proteolysis [NCIt concept]

Keyword's position in hierarchy(ies) :

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