Preferred Label : CCL18 wt Allele;
NCIt synonyms : MIP-4; DCCK1; PARC; SCYA18; AMAC-1; CKb7; AMAC1; Chemokine (C-C Motif) Ligand 18 Gene; DC-CK1; Chemokine (C-C Motif) Ligand 18 (Pulmonary and Activation-Regulated) wt Allele; MIP4;
NCIt definition : Human CCL18 wild-type allele is located in the vicinity of 17q11.2 and is approximately
7 kb in length. This allele, which encodes C-C motif chemokine 18 protein, is involved
in the chemotactic regulation of naive T cells, CD4 and CD8 T cells, and nonactivated
lymphocytes involved in inflammatory processes. CCL18 allele may also be involved
in B cell migration into lymph node follicles as well as humoral and cell-mediated
immunity.;
NCIt note : CCL18 is induced by glucocorticoids, PMA, IL-4, IL-13, and IL-10 and expressed in
lung, lymph nodes, placenta, bone marrow, dendritic cells, and macrophages.;
GenBank Accession Number : NM_002988;
Origin ID : C49723;
UMLS CUI : C1706483;
OMIM relation
- Semantic type(s)
- concept_is_in_subset
- gene_found_in_organism
- gene_has_physical_location
- gene_in_chromosomal_location
- gene_is_element_in_pathway
- gene_plays_role_in_process
