FURIN wt Allele

Preferred Label : FURIN wt Allele;

NCIt synonyms : Furin (Paired Basic Amino Acid Cleaving Enzyme) wt Allele; Paired Basic Amino Acid Cleaving Enzyme Gene; PACE Gene; FUR; SPC1; PCSK3;

NCIt definition : Human FURIN wild-type allele is located in the vicinity of 15q26.1 and is approximately 15 kb in length. This allele, which encodes furin protein, plays a role in the cleavage of proteins containing paired basic amino-acid residues to release mature proteins from their precursor proteins.;

GenBank Accession Number : NM_002569;

Details

Origin ID

C49715;

UMLS CUI

C1704661;

OMIM relation
- Furin, paired basic amino acid cleaving enzyme [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 15: 89212889-89227691 [NCIt concept]
gene_in_chromosomal_location
- 15q26.1 [NCIt concept]
gene_is_element_in_pathway
- Glypican 3 Signaling Pathway [NCIt concept]
- HIF-1-Alpha Transcription Factor Pathway [NCIt concept]
- Nerve Growth Factor Receptor Signaling Pathway [NCIt concept]
- Notch Proteolysis and Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Hydrolysis [NCIt concept]
- Post-Translational Modification [NCIt concept]
- Proteolysis [NCIt concept]
- Proteolytic Processing [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients