PTPRJ wt Allele

Preferred Label : PTPRJ wt Allele;

NCIt synonyms : Protein Tyrosine Phosphatase, Receptor Type, J wt Allele; DEP1; R-PTP-ETA; SCC1; CD148; HPTPeta;

NCIt definition : Human PTPRJ wild-type allele is located in the vicinity of 11p11.2 and is approximately 188 kb in length. This allele, which encodes receptor-type tyrosine-protein phosphatase eta protein, is involved in the dephosphorylation of protein-tyrosine phosphates. Defects in the PTPRJ gene are associated with several types of cancer such as breast, colon and lung cancers.;

GenBank Accession Number : NM_002843;

Details

Origin ID

C49537;

UMLS CUI

C1704792;

OMIM relation
- Protein-tyrosine phosphatase, receptor-type, j [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_associated_with_disease
- Colon Carcinoma [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 11p11.2 [NCIt concept]
gene_is_element_in_pathway
- Adherens Junction Assembly Pathway [NCIt concept]
- Hepatocyte Growth Factor Receptor Signaling Pathway PID [NCIt concept]
- PDGFR-beta Signaling Pathway [NCIt concept]
- Phosphatidylinositol Signaling System Pathway [NCIt concept]
gene_plays_role_in_process
- Dephosphorylation [NCIt concept]
- Hydrolysis [NCIt concept]
- Protein Dephosphorylation [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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