NUDT1 wt Allele

Preferred Label : NUDT1 wt Allele;

NCIt synonyms : MutT Human Homolog 1 Gene; MTH1; Nudix Hydrolase 1 wt Allele; Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 1 Gene;

NCIt definition : Human NUDT1 wild-type allele is located within 7p22 and is approximately 9 kb in length. This allele, which encodes oxidized purine nucleoside triphosphate hydrolase protein, is involved in the hydrolysis of 8-oxo-dGTP in the free nucleotide pool. Overexpression of the NUDT1 gene is associated with several types of cancer such as non-small-cell lung carcinomas, renal cell carcinomas and prostate cancer.;

GenBank Accession Number : NM_198949;

Details

Origin ID

C49415;

UMLS CUI

C1709143;

OMIM relation
- Nudix hydrolase 1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 7p22 [NCIt concept]
gene_plays_role_in_process
- Detoxification [NCIt concept]
- Hydrolysis [NCIt concept]
- Nucleotide Metabolic Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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