NCIt definition : A small molecule compound with potential antineoplastic activities. BI 2536 binds
to and inhibits Polo-like kinase 1 (Plk1), resulting in mitotic arrest, disruption
of cytokinesis, and apoptosis in susceptible tumor cell populations. Plk1, a serine/threonine-protein
kinase, is a key regulator of multiple processes fundamental to mitosis and cell division.;
Alternative definition : NCI-GLOSS: A substance being studied in the treatment of cancer. It prevents cells
from dividing and may block the growth of some tumors. It is a type of mitotic inhibitor.;
UNII : 4LJG22T9C6;
CAS number : 755038-02-9; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 755038-02-9
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