Melanoma Tumor-Reactive Autologous Tumor Infiltrating Lymphocyte

Preferred Label : Melanoma Tumor-Reactive Autologous Tumor Infiltrating Lymphocyte;

NCIt synonyms : Melanoma Tumor-Reactive Autologous Tumor Infiltrating Lymphocytes (TIL); Melanoma Tumor-Reactive Autologous TIL; Melanoma Tumor-Reactive Autologous Tumor Infiltrating Lymphocytes;

NCIt definition : Tumor infiltrating lymphocytes (TIL) harvested directly from infiltrate of a patient's melanoma and cultured with interleukin-2 to expand the TIL cell population. Tumor infiltrating lymphocytes have specific activity against the melanoma from which they are derived. Introducing these melanoma tumor-reactive autologous tumor infiltrating lymphocytes back into the same patient may enhance a cytotoxic T-cell-mediated immune response against the melanoma cancer cells.;

NSC code : 733610;

Details

Origin ID

C48814;

UMLS CUI

C1708978;

Semantic type(s)
- Cell [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_affects_cell_type_or_tissue
- Cytotoxic T-Lymphocyte [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Sensitization [NCIt concept]
chemical_or_drug_has_physiologic_effect
- Immunopotentiation [NCIt concept]
- T-Cell Activation [NCIt concept]

Keyword's position in hierarchy(ies) :

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