" /> Zibotentan - CISMeF





Preferred Label : Zibotentan;

NCIt synonyms : 3-Pyridinesulfonamide, N-(3-methoxy-5-methylpyrazinyl)-2-(4-(1,3,4-oxadiazol-2-yl)phenyl)-; N-(3-methoxy-5-methylpyrazin-2-yl)-2-[4-(1,3,4-oxadiazol-2-yl)phenyl]pridine-3- sulfonamide; ZD-4054;

NCIt related terms : ZD4054;

NCIt definition : An orally available selective antagonist of the endothelin-A (ET-A) receptor with potential antineoplastic activity. Zibotentan binds selectively to the ET-A receptor, thereby inhibiting endothelin-mediated mechanisms that promote tumor cell proliferation.;

Alternative definition : NCI-GLOSS: A substance that is being studied in the treatment of prostate cancer. It belongs to the family of drugs called endothelin-receptor antagonists.;

UNII : 8054MM4902;

InChIKey : FJHHZXWJVIEFGJ-UHFFFAOYSA-N;

CAS number : 186497-07-4; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 186497-07-4 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : ZD4054;

Chemical formula : C19H16N6O4S;

Codes from synonyms : CDR0000430878;

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12/05/2024


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