NCIt definition : A humanized monoclonal antibody directed against the CD20 antigen with potential antineoplastic
activity. Following binding, veltuzumab triggers complement-dependent cell lysis (CDCL)
and antibody-dependent cell-mediated cytotoxicity (ADCC) in cells that overexpress
CD20. CD20 antigen is a hydrophobic transmembrane protein located on pre-B and mature
B lymphocytes.;
Alternative definition : NCI-GLOSS: A substance being studied in the treatment of several types of lymphoma.
It binds to the protein CD20, which is found on B cells (a type of immune system cell)
and some types of lymphoma cells. This causes the immune system to kill the cancer
cells. IMMU-106 is a type of monoclonal antibody.;
UNII : BPD4DGQ314;
CAS number : 728917-18-8; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 728917-18-8
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G-SRS /a ;
Molecule name : IMMU-106;
Codes from synonyms : CDR0000662028; CDR0000443694; CDR0000438728; CDR0000438729; 532;