Veltuzumab - CISMeF

Preferred Label : Veltuzumab;

NCIt synonyms : Anti-CD20 Monoclonal Antibody hA20; Monoclonal Antibody hA20; MoAb hA20;

NCIt related terms : HCD20; IMMU-106; hA20;

NCIt definition : A humanized monoclonal antibody directed against the CD20 antigen with potential antineoplastic activity. Following binding, veltuzumab triggers complement-dependent cell lysis (CDCL) and antibody-dependent cell-mediated cytotoxicity (ADCC) in cells that overexpress CD20. CD20 antigen is a hydrophobic transmembrane protein located on pre-B and mature B lymphocytes.;

Alternative definition : NCI-GLOSS: A substance being studied in the treatment of several types of lymphoma. It binds to the protein CD20, which is found on B cells (a type of immune system cell) and some types of lymphoma cells. This causes the immune system to kill the cancer cells. IMMU-106 is a type of monoclonal antibody.;

UNII : BPD4DGQ314;

CAS number : 728917-18-8;

Molecule name : IMMU-106;

Codes from synonyms : CDR0000662028; CDR0000443694; CDR0000438728; CDR0000438729; 532;

Details

Origin ID

C48406;

UMLS CUI

C2746054;

Currated CISMeF NLP mapping
- veltuzumab [MeSH Supplementary Concept]
- veltuzumab [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- veltuzumab [MeSH Supplementary Concept]
- veltuzumab [MeSH concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Binding [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- HemOnc Agent Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- B-Lymphocyte Antigen CD20 [NCIt concept]

Keyword's position in hierarchy(ies) :

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