Therapeutic Estrone

Preferred Label : Therapeutic Estrone;

NCIt synonyms : Oestrone;

NCIt related terms : Theelin; ESTRONE;

NCIt definition : The synthetic form of a naturally occurring estrogen estrone. Estrone diffuses through the cell membrane and binds to and subsequently activates the nuclear estrogen receptor found in the reproductive tract, breast, pituitary, hypothalamus, liver, and bone. The activated hormone-receptor complex gets translocated to the nucleus where it binds to the estrogen response element on the DNA and promotes the transcription of target genes involved in the functioning of the female reproductive system and secondary sex characteristics. Estrone increases the hepatic synthesis of sex hormone binding globulin (SHBG), thyroid-binding globulin (TBG), and other serum proteins, as well as suppresses the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary.;

UNII : 2DI9HA706A;

InChIKey : DNXHEGUUPJUMQT-CBZIJGRNSA-N;

CAS number : 53-16-7; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 53-16-7 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Chemical formula : C18H22O2;

NCI Metathesaurus CUI : CL1773622;

NSC code : 9699;

ChEBI ID : CHEBI:17263;

Codes from synonyms : NSC0009699; 01201;

Details

Origin ID

C484;

UMLS CUI

C4721526;

See also inter- (CISMeF)
- Estrone [MedDRA LLT]
- Oestrone [MedDRA Preferred Term]
Semantic type(s)
- Hormone [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Estrone [LOINC component]
- Estrone (substance) [SNOMED CT concept]
- Product containing estrone (medicinal product) [SNOMED CT concept]
- estrone [ATC Code]
- estrone [ATC Code]
- estrone [MeSH concept]
- estrone [MeSH Descriptor]
- estrone [SNOMED Notion]
- estrone preparation [SNOMED Notion]
Validated automatic mappings to BTNT
- estrone [ATC Code]
- estrone [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Esterified Estrogens [NCIt concept]
- Estrone Sodium Sulfate [NCIt concept]
- Estrone Sulfate [NCIt concept]
is_free_acid_or_base_form_of
- Esterified Estrogens [NCIt concept]
- Estrone Sodium Sulfate [NCIt concept]
- Estrone Sulfate [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients