NCIt definition : A mixture of the sodium salts of the sulfate esters of estrogen including sodium estrone
sulfate, sodium equilin sulfate and the concomitant component, 17 alpha-estradiol,
that is used for estrogen replacement. Estrogens bind to nuclear receptors in estrogen-responsive
tissues and modulate the secretion of the gonadotropins, luteinizing hormone (LH)
and follicle-stimulating hormone (FSH), stimulate skeletal growth, and have a widespread
effect on metabolic processes including protein transport and electrolyte balance.;